SeesmicAIR is still currently only configured to run on Beta 3 or Adobe’s AIR platform. If you download the latest version from Adobe, SeesmicAIR will not run properly. You will need (until I update it) to use Beta 3 of Adobe’s AIR, which can be found at right here.

I do plan on having it updated to AIR 1.0 this weekend. I apologize for the delay.. things have just been a tad busy with the job switch over.